DIAGNOSIS AND MONITORING
Diagnosis and Monitoring Involve Symptomology as Well as Lab Values1,2
Biochemical
- Serum calcium: levels below the lower limits of normal range confirmed on ≥ 2 measures help establish the diagnosis1*†
- Serum PTH: low or inappropriately normal levels (ie, < 20 pg/mL) in the presence of hypocalcemia on ≥ 2 measures help establish the diagnosis1,2†
- Serum phosphate: levels in the upper normal or obviously elevated range may be helpful in diagnosis and evaluation1
- 24-hour urinary calcium excretion: used along with estimated or calculated GFR and biochemical nephrolithiasis risk profile (if clinically warranted)1
Additional Evaluations
- Patient-reported outcome measures1,3
- Medical and family history1
- Physical examination1
- Target-organ imaging1
- Genetic testing1‡
